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Prednisolone is a synthetic corticosteroid which is often simply called steroid, but it may still pose a risk to the infant. Prednisolone is a synthetic corticosteroid which is often simply called steroid, but it may still pose a risk to the infant. Prednisone is used in much higher doses than the levels of corticosteroids produced naturally by the body, and as such, the usual actions of corticosteroids become exaggerated and may be observed as side effects of this medicine.